06/27/2025 2:44 p.m.

Everything you need to know about the transition to menopause

Dr. Niels van de Roemer
Dr. Niels van de Roemer Medical Adviser
The Transition to a New Phase of Life

What is Menopause?

Menopause is a natural biological process in every woman's life that marks the end of fertility. From a medical perspective, menopause is defined as the point when a woman experiences her last menstrual period and no further bleeding occurs for at least 12 consecutive months. The time surrounding menopause is known as the climacteric, which includes several stages: premenopause, perimenopause, and postmenopause.

Typically, menopause occurs between the ages of 45 and 55, although individual variations are common. The hormonal changes that take place during these years affect not only the menstrual cycle but also have a significant impact on numerous physical and psychological processes.

An overview

The Phases of Menopause

Although in everyday language we often refer to the term “menopause” as a long phase, from a medical standpoint, menopause itself is technically just a single day—the exact point of the last spontaneous menstrual period, after which no bleeding occurs for at least twelve consecutive months. Everything that happens before and after this moment is classified into the different stages of hormonal transition.

This transitional period extends over several years and is divided into perimenopause, menopause, and postmenopause. Each stage brings its own physical and emotional changes, and understanding these phases helps women navigate this time more effectively and take an active role in managing their well-being.

The onset of hormonal changes

Perimenopause

Perimenopause begins several years before menopause, typically in a woman’s early to mid-40s. During this period, estrogen levels start to fluctuate and decline, leading to irregular menstrual cycles and a variety of physical and emotional symptoms. Women may notice hot flashes, night sweats, mood swings, and sleep disturbances.

Some cycles may occur without ovulation, and periods can become either heavier or lighter. The perimenopausal stage is also when many women start to observe changes in metabolism, weight gain, or a decrease in bone density. Tracking these changes can help women better understand and manage this transitional stage.

The turning point

Menopause

Menopause itself is a single point in time—the final menstrual period. However, this is only determined retrospectively, after a woman has gone 12 months without a period. By this point, the ovaries have significantly reduced hormone production, and reproductive capability has come to an end.

During this phase, many women experience heightened symptoms such as increased hot flashes, vaginal dryness, and changes in libido. These are primarily driven by the drop in estrogen and progesterone levels, which play key roles in regulating bodily systems, including the reproductive cycle, bone health, and cardiovascular function.

Life after menstruation

Postmenopause

The postmenopausal stage begins one year after menopause and lasts for the rest of a woman’s life. While some symptoms like hot flashes and night sweats may lessen over time, low hormone levels remain, increasing the risk of certain health conditions. These may include osteoporosis, heart disease, and reduced skin elasticity.

Lifestyle changes, nutritional support, and, in some cases, medical treatments can help women maintain vitality and health during this stage. Understanding the body’s new hormonal balance is key to living well after menopause.

A look behind the scenes

Hormonal Changes During Menopause

The menopausal transition is not only a time of outward changes—profound hormonal shifts occur within the body, affecting nearly every system. The ovaries and the interaction of female sex hormones undergo fundamental changes. The hormonal balance, which has regulated the menstrual cycle for decades, begins to fluctuate and eventually resets permanently.

To better understand the typical symptoms and side effects of menopause, it is essential to take a closer look at the hormonal processes that occur during this stage.

Before Menopause (Reproductive Years):

  • Each month, follicles mature in the ovaries.
  • The pituitary gland (hypophysis) releases LH (luteinizing hormone) and FSH (follicle-stimulating hormone).
  • These hormones stimulate the production of estrogen.
  • Estrogen builds up the uterine lining and, once it reaches a certain level, triggers ovulation.

After Ovulation:

  • The corpus luteum (yellow body) produces progesterone.
  • Progesterone prepares the uterine lining for a potential pregnancy.
  • If no fertilization occurs, progesterone levels drop, and menstruation begins.

With Increasing Age:

  • The ovaries become less responsive to LH and FSH.
  • The number of follicles declines drastically (about 1,000 left compared to approximately 250,000 at puberty).
  • Estrogen production fluctuates, and ovulation becomes less frequent.
  • The body attempts to compensate by significantly increasing FSH levels.

Hormonal Imbalance:

  • A relative estrogen dominance occurs.
  • At the same time, there is a progesterone deficiency.
  • This imbalance is the main cause of many menopausal symptoms (e.g., hot flashes, mood swings).

After Menopause:

  • Hormone levels stabilize at a consistently low level.
  • Only small amounts of estrogen and progesterone remain in the body.
  • The menstrual cycle ceases permanently, marking the end of fertility.
A Delicate Balance

The Role of Progesterone and Estrogen

Estrogen plays a key role in the development of the uterine lining. It also promotes overall well-being, supports firm connective tissue, aids bone metabolism, and protects blood vessels.

Progesterone, produced by the corpus luteum (yellow body) after ovulation, has a calming and sleep-promoting effect. It balances the effects of estrogen and prepares the body for a potential pregnancy.

During perimenopause, progesterone levels often drop faster than estrogen levels. The result is a relative estrogen dominance, which can lead to menstrual irregularities and cycle anomalies.

What Many Women Experience

Symptoms of Menopause

The intensity and duration of menopausal symptoms vary greatly among women and depend on factors such as genetics, lifestyle, and stress levels. Common symptoms include:

  • Hot flashes and night sweats
  • Mood swings and irritability
  • Sleep disturbances and fatigue
  • Weight gain, especially around the abdomen
  • Dry skin and mucous membranes
  • Reduced libido
  • Difficulty concentrating and memory lapses
  • Heart palpitations or rapid heartbeat
  • Irregular menstrual cycles and heavier bleeding

Natural and Medical Approaches for Menopause Support

Lifestyle Adjustments

  • Balanced diet rich in phytoestrogens (e.g., soy, flaxseeds)
  • Regular physical activity to boost metabolism and support bone health
  • Stress reduction techniques such as meditation, yoga, or breathing exercises

Hormone Replacement Therapy (HRT)

In cases where menopausal symptoms are particularly severe, personalized hormone replacement therapy can be an effective way to alleviate discomfort by replenishing declining hormone levels. However, while HRT has shown promising results for many women, more research is still needed to fully understand its long-term effects and safety.

This treatment option should always be carefully evaluated on an individual basis, weighing potential benefits against possible risks. A thorough discussion with a qualified gynecologist or healthcare provider is essential to determine whether HRT is a suitable and safe choice. For many women, it can represent a highly effective possibility for improving quality of life during menopause.

Herbal and Natural Remedies

Many women turn to plant-based supplements for relief from menopausal symptoms. Popular options include:

  • Black cohosh – commonly used for hot flashes and night sweats.
  • Chaste tree (Vitex agnus-castus) – known for regulating hormonal fluctuations.
  • St. John’s wort – often used to relieve mood swings and mild depression.

While scientific evidence varies, many report positive effects from these natural remedies, especially when combined with a healthy lifestyle.

Empowering Women Through Menopause with Daysy and Lady-Comp

Navigating menopause can be challenging, but Daysy and Lady-Comp's intelligent tracking helps women gain a clear understanding of their hormonal patterns and how their bodies are changing during this life stage. By monitoring these shifts, these devices enable women to identify trends, anticipate symptoms, and make informed health decisions.

With its advanced algorithm and personalized insights, Daysy and Lady-Comp empower women to take control of their reproductive health, easing the uncertainty that often accompanies menopause. Beyond cycle tracking, it promotes self-awareness and body literacy, helping women embrace this transition with confidence, balance, and peace of mind.

Understanding Perimenopause with Daysy

The perimenopausal stage is often the most unpredictable phase of the transition, as hormone levels—especially estrogen and progesterone—fluctuate dramatically. During this time, many women experience a shift in focus from fertility to an awareness of their body’s natural evolution toward infertility. Daysy plays a crucial role by offering a clear and real-time overview of these hormonal changes, helping women better understand what is happening beneath the surface.

By tracking temperature patterns and interpreting hormonal data, Daysy provides insights that go beyond what a traditional calendar or symptom diary can offer. This scientific yet intuitive approach allows women to see exactly how their bodies are responding as they approach menopause. While Daysy cannot predict the exact timing of menopause, it can provide valuable indicators of when ovulation is becoming irregular or when cycles begin to shorten or lengthen, both of which are common in perimenopause.

This knowledge-based approach allows women to make proactive decisions about their health, whether that means discussing hormonal changes with a healthcare provider, adjusting their lifestyle to accommodate new symptoms, or simply understanding that the changes they are experiencing are part of a natural, healthy process. By fostering body awareness and education, Daysy helps women approach perimenopause with confidence, acceptance, and actionable knowledge.

Menopause is Not an End – But a New Beginning

Menopause represents a profound yet natural transformation in every woman’s life. It offers an opportunity to rediscover and understand the body, provide it with the support it needs, and step into a new phase of life with strength and confidence.

FAQs

When Does Menopause Begin and How Long Does It Last?

Menopause itself is a single day—the exact point of the last menstrual period. It is determined retrospectively once 12 consecutive months have passed without any menstrual bleeding. However, hormonal changes often begin years earlier during perimenopause and can span a total of 5 to 10 years.

Can I Still Get Pregnant During Perimenopause?

Yes, pregnancy is still possible during perimenopause, even if menstrual cycles are irregular. Ovulation can still occur sporadically, so contraception is necessary until 12 months have passed without a period to ensure that fertility has completely ceased.

Should I Take Hormones – Yes or No?

The decision to start hormone replacement therapy (HRT) depends on individual circumstances, the severity of symptoms, and potential risks such as thrombosis, breast cancer, or high blood pressure. In cases of severe symptoms, a low-dose, time-limited HRT can offer significant relief.

It is essential that therapy is personally tailored and supervised by a gynecologist. Alternatives to HRT include herbal supplements, lifestyle adjustments, and targeted nutrient intake to manage symptoms naturally.

Richardson SJ et al. Follicular depletation during the menopausal transition: evidence for accelerated loss and ultimate exhaustion. J Clin Endocrinol Metab 1987;65:1231-1237

Learn more

Low progesterone can cause fatigue, irregular cycles, and fertility issues. Learn how to spot it and boost levels naturally.

Perimenopause is the often-overlooked transition before menopause, marked by hormonal shifts and unpredictable cycles. Learn how to recognize the signs, manage symptoms, and regain clarity with practical tools like cycle tracking.

The female cycle is regulated and influenced by a finely tuned interaction of various hormones.