05/19/2025 1:43 p.m.

Understanding Perimenopause And What Happens Before Menopause

Dr. Niels van de Roemer
Dr. Niels van de Roemer Medical Adviser
Transition to menopause

What Is Perimenopause?

Perimenopause marks an essential transitional phase in a woman's life, during which female hormone levels gradually decline. This period is characterized by changes in the menstrual cycle, hormonal fluctuations, and both physical and emotional symptoms. While some women experience these changes for only a few months, for others, perimenopause can last for several years—on average, around four to five years.

Perimenopause refers to the period before menopause, when the female reproductive system gradually reduces its hormonal activity. The ovaries produce less estrogen and progesterone, leading to shorter, irregular cycles and fewer ovulatory phases. Early in perimenopause, the follicular maturation phase shortens, causing shorter cycles. In later stages, ovulation often stops altogether, and menstrual periods may become irregular or stop entirely.

Perimenopause is a natural and normal process, but it affects every woman differently. Understanding what happens during this time is key to managing both physical and emotional changes effectively.

What Is the Difference Between Perimenopause and Menopause?

Menopause is defined as the point of a woman's last menstrual period, confirmed after 12 consecutive months without menstruation. Perimenopause, on the other hand, is the transition phase leading up to menopause. Menopause typically occurs between the ages of 45 and 55, but experiences vary widely among women. The transition is often gradual, with perimenopause and menopause phases blending seamlessly into each other.

The number of follicles decreases

How Do Menstrual Cycles Change During Perimenopause?

As women age, the ovaries respond less effectively to hormonal signals. This is primarily due to the declining number of follicles, which are the small sacs in the ovaries that release eggs each month. While a woman has around 250,000 follicles per ovary after puberty, only about 1,000 remain by the time menopause approaches.

The reduced follicle reserve causes the body to produce higher levels of follicle-stimulating hormone (FSH) to encourage the maturation of remaining follicles. This overproduction of FSH often results in increased estrogen production, but with a simultaneous relative progesterone deficiency, creating hormonal imbalances. These imbalances are responsible for many common perimenopause symptoms, such as mood swings, sleep disturbances, and irregular bleeding.

Ovulatory vs. Anovulatory Cycles

During perimenopause, two types of menstrual cycles can occur:

  1. Ovulatory Cycles

  • Follicles respond to hormonal signals
  • Ovulation is triggered
  • Typically, early ovulation occurs, leading to a cycle shortened by 2–4 days
  • Heavier menstrual bleeding
More

In an ovulatory cycle, the follicles respond to hormonal signals: estrogen levels rise, and the luteinizing hormone (LH) triggers ovulation. One of the earliest signs that the body is entering perimenopause is often a shortening of the menstrual cycle by about 2 to 4 days.

The reason for this lies in a changed response of the ovaries. They become more sensitive to the follicle-stimulating hormone (FSH), which is produced in higher amounts during this stage of life. This increased sensitivity can lead to earlier ovulation and, as a result, a shorter cycle.

At the same time, progesterone levels gradually decline. This can lead to heavier menstrual bleeding, regardless of how high estrogen levels are. It is important to know that even if the cycle changes, this often still represents a “true menstruation”, meaning a bleeding that follows ovulation. This can be identified by a rise in basal body temperature about 10 to 16 days before the bleeding. These first changes, especially the shortening of cycles, are typical early signs of perimenopause.

A final note: Shorter cycles can have other causes as well. If you notice a slightly shorter cycle in your 30s, it does not automatically mean you are already in perimenopause. In fact, the average cycle length naturally shortens with age – from around 29 days in your 20s to about 26 days in your 40s.

  1. Anovulatory Cycles

  • Follicles do not respond to the hormonal surge
  • Estrogen levels remain low
  • Ovulation does not occur
  • No increase in basal body temperature
  • Cycle ends with a shorter breakthrough bleeding
More

The follicles do not respond, which results in low estrogen levels, and no ovulation occurs. In contrast to a cycle with ovulation, there is no temperature rise during the luteal phase in an anovulatory cycle due to the lack of ovarian response, and the cycle usually ends with a somewhat shorter breakthrough bleeding.

The bleeding that occurs after an anovulatory cycle is technically not a "real" menstruation but an estrogen breakthrough bleeding. It is caused by low progesterone levels and the buildup of the uterine lining. You can identify an anovulatory cycle by tracking your basal body temperature with a cycle monitor such as Daysy. If you do not detect a rise in your basal body temperature, it means ovulation has not taken place.

On average, about 6 out of the last 10 cycles in the year before menopause are anovulatory. This means that in this late stage of perimenopause, approximately 60% of cycles may occur without ovulation.

How Does Menstruation Change in Perimenopause?

Menstrual flow and intensity can vary significantly during perimenopause.

In anovulatory cycles, bleeding may be lighter, shorter, or absent altogether.

During ovulatory cycles, the bleeding can be heavier than usual. Research shows that in the late transition phase (one to three years before menopause), the average blood loss during menstruation after ovulatory cycles is more than double compared to a woman's earlier fertile years.

Common Symptoms and Changes During Perimenopause

Perimenopause is accompanied by a range of symptoms, many of which are caused by hormonal fluctuations. The most common include:

  1. Irregular Menstrual Cycles

During perimenopause, menstrual cycles can become irregular. Some women may experience longer or shorter cycles, heavier or lighter bleeding. Some cycles may even occur without ovulation.

  1. Hot Flashes and Night Sweats

These are perhaps the most-known symptoms of perimenopause and menopause. Hot flashes can cause sudden feelings of heat in the upper body, often accompanied by flushing and sweating. Night sweats can lead to sleep disturbances.

  1. Mood Swings

Many women report mood swings, irritability, or depression during perimenopause. This can be partly due to hormonal changes but also linked to sleep problems caused by night sweats.

  1. Sleep Disturbances

Difficulties falling asleep or staying asleep can occur during perimenopause, often in connection with night sweats.

  1. Changes in Libido

Some women experience reduced libido or changes in sexual response and sensation. Vaginal health may also be affected, with symptoms such as dryness or discomfort during intercourse.

  1. Cognitive Changes

Some women report concentration difficulties or memory problems during perimenopause.

  1. Physical Changes

Physical changes such as weight gain and changes in fat distribution can occur.

How to Manage Perimenopause Symptoms?

It is important to understand that perimenopause is a normal transitional process that can last for several years. As a first step, it can be very helpful to become familiar with this phase, track symptoms, and monitor basal body temperature to better understand what is happening in your body.

When dealing with the symptoms described, a holistic and individualized approach is particularly important. Since every woman experiences perimenopause differently, it is crucial to address specific symptoms while considering overall health. A balanced diet, regular physical activity, and adequate sleep can be the first steps in alleviating individual symptoms.

If you are suffering from severe symptoms that significantly affect your quality of life, medical treatment may be necessary—such as hormone therapy to relieve intense hot flashes or the use of sleep aids for insomnia caused by menopausal changes.

  1. Relief from Hot Flashes

When experiencing hot flashes, dressing in layers can be very helpful. By wearing multiple layers of clothing, you can remove one layer when necessary to cool your body down. Once the hot flash is over, you can put the layer back on. This is particularly useful because a hot flash is often followed by a sudden feeling of chill. After a hot flash, a functional undershirt that does not absorb moisture may feel more comfortable than cotton underwear.

  1. When Weight Changes

During perimenopause, a phase already marked by hormonal fluctuations, many women find it more challenging to maintain their weight. This can be frustrating, but it is not a sign of failure; rather, it is part of a complex physical transition process. During this time, it can be especially helpful to listen to your body and provide what it needs, for example:

  • A nutrient-rich diet with plenty of vegetables, fruits, healthy fats, and sufficient protein.
  • Physical activity that you enjoy, whether it’s walking, yoga, dancing, or strength training.

  1. Gentle Sleep Despite Hormonal Chaos

Sleep disturbances are common during perimenopause due to hormonal fluctuations and symptoms such as hot flashes and night sweats. Here are some strategies that can help:

  • Good Sleep Hygiene: Try to maintain a regular bedtime and create a quiet, dark, and cool sleep environment. Avoid screens and electronic devices shortly before bedtime, as the light from these devices can disrupt sleep.
  • Relaxation Techniques: Practices like yoga, meditation, or breathing exercises can calm the mind and promote relaxation before bed.
  • Exercise: Regular physical activity can improve sleep quality. However, avoid intense workouts right before bedtime, as the adrenaline released can cause additional restlessness.
  • Avoid Heavy Meals and Alcohol Before Bed: Both can disturb sleep and cause discomfort or digestive problems.

  1. When Your Body Needs More – Helpful Vitamins for Perimenopause

Although there are no vitamins exclusively for perimenopause, certain nutrients can be beneficial:

  • Calcium – essential for bone health.
  • Vitamin D – supports calcium absorption.
  • Vitamin K – plays a role in bone health and blood clotting.
  • Vitamin E – may help alleviate hot flashes and other menopausal symptoms.
  • B Vitamins, especially B6 – support hormone regulation and mood balance.
  • Magnesium – can help reduce muscle cramps and sleep disturbances.

  1. Alternative Remedies – Using Natural Therapies During Menopause

In recent years, alternative therapies for menopause have gained popularity. One notable approach comes from menopause expert Lara Briden, a well-known author and health specialist focusing on hormonal health. Her recommendations are based on naturopathic principles and a holistic approach to menopause. She suggests:

  • Maintaining a balanced diet.
  • Engaging in regular physical activity.
  • Practicing stress management.

Additionally, Lara Briden highlights the benefits of herbal remedies for symptoms such as hot flashes and mood swings, including:

  • Black cohosh.
  • Chaste tree berry (Vitex).

If you are considering alternative therapies, you should consult with a healthcare professional to discuss potential interactions with other medications or health conditions.

  1. Hormone Replacement Therapy (HRT)

other widely used treatment for severe menopausal symptoms is hormone replacement therapy (HRT). This therapy involves taking synthetic hormones, particularly estrogen and progesterone, to compensate for hormonal deficiencies during menopause. HRT can be administered in different forms:

  • Tablets
  • Patches
  • Gels
  • Injections

HRT can be highly effective in alleviating symptoms like hot flashes, night sweats, vaginal dryness, and sleep disturbances. It can also slow down bone loss (osteoporosis) that often accompanies menopause.

However, it is crucial to understand that HRT carries potential risks and side effects. Therefore, it is recommended to consult with a doctor to evaluate the individual benefits and risks and to tailor the therapy to your specific needs.

7. Cycle Tracking – Your Tool for More Clarity During Perimenopause

Cycle tracking can be a valuable support during perimenopause to better understand the changes happening in your body.

By regularly observing and recording your cycle, you can identify patterns in your menstrual cycle and accompanying symptoms such as hot flashes, sleep disturbances, or mood swings. It also allows you to see whether you are producing enough progesterone, as a sustained rise in basal body temperature indicates adequate progesterone levels after ovulation. You can also recognize when you have an anovulatory cycle (a cycle without ovulation).

This provides you with valuable insights into your hormonal state and helps you cope more effectively with the fluctuations occurring during this transitional phase.

FAQs

What are the first signs of perimenopause?

The first signs of perimenopause can include irregular periods, changes in menstrual flow, mood swings, hot flashes, and sleep problems. These symptoms vary greatly from woman to woman and may develop gradually or appear suddenly. By tracking your cycle, you can detect changes such as shortened cycles or anovulatory cycles (cycles without ovulation) at an early stage.

Can I get pregnant during perimenopause?

Yes, pregnancy is still possible during perimenopause, as ovulation does not stop completely at the beginning. However, since cycles become increasingly irregular, using a cycle monitor can help track ovulation and keep an eye on your cycle.

When should I see a doctor about perimenopause?

If the symptoms of perimenopause significantly affect your quality of life – for example, persistent insomnia, depressive moods, severe mood swings, or intense hot flashes – it is advisable to seek medical advice. A gynecologist or healthcare professional can advise you on possible treatments, such as hormonal therapy or alternative remedies.

How can cycle tracking help me during perimenopause?

Cycle tracking is especially valuable during perimenopause because it helps you better understand and monitor the changes in your hormonal balance. During this transitional phase, cycles often become irregular, and ovulation can become unpredictable. By recording cycle length, basal body temperature, and symptoms, you can determine if and when ovulation occurs, whether you are producing enough progesterone, and how your cycle changes over time.

This not only provides you with a better understanding of your body but can also be crucial if you want to avoid pregnancy or plan one intentionally. Furthermore, the data you collect can provide important insights for your doctor, enabling more targeted discussions about possible treatments or therapeutic options.

Sources

1) Prior JC. Perimenopause: the complex endocrinology of the menopausal transition. Endocrine Reviews. 1998 Aug;19(4):397-428.
https://academic.oup.com/edrv/article/19/4/397/2530801

2) Hale, G. E., Manconi, F., Luscombe, G., and Fraser, I. S. Quantitative measurements of menstrual blood loss in ovulatory and anovulatory cycles in middle- and late-reproductive age and the menopausal transition. Obstetrics and Gynecology , 115(2 Pt 1):249–256, Feb 2010
​​https://pubmed.ncbi.nlm.nih.gov/20093896/

3) Landgren BM, Collins A, Csemiczky G, Burger HG, Baksheev L, Robertson DM. Menopause transition: annual changes in serum hormonal patterns over the menstrual cycle in women during a nine-year period prior to menopause. The Journal of Clinical Endocrinology & Metabolism. 2004 Jun 1;89(6):2763-9.
https://pubmed.ncbi.nlm.nih.gov/15181055/

4) https://www.larabriden.com/category/perimenopause-menopause/

Learn more

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